The Lumière brothers, Auguste and Louis Jean, are credited as the fathers of cinematography. At the "Grand Cafe" in Paris in 1895, they unveiled for the first time their cinematograph, a technical innovation that revolutionized the nascent motion picture. It was the first public projection of a film. While Louis continued his work on pictures and invented autochrome plates for colour photography, his brother focused his interests on biology and medicine. Auguste was a pioneer in the modern research and treatment of wounds and in 1915 he perfected a revolutionary sterilized "treatment-bandage". When Auguste Lumière died in 1954 he had registered more than one hundred patents.