Portrait an Anne Blythe (1536-1615), wife of Peter Osborn, bust-length, in a black dress with a ruff and gold chain

Anne was the daughter of Dr. John Blythe, regius professor of physics at Cambridge, and niece of Sir John Cheke. By 1551 she had married Peter Osborne (1521–1592), who in 1551–2 was Keeper of the Privy Purse to King Edward VI and in 1552 held the office of Remembrancer to the Lord-Treasurer in the Exchequer. They had numerous children and one of their sons, Sir Peter Osborne (1584–1653) was appointed Lieutenant-Governor of Guernsey in 1621.